The effects of creatine ethyl ester supplementation combined with heavy
resistance training on body composition, muscle performance, and serum and
muscle creatine levels

Journal of the International Society of Sports Nutrition 2009, 6:6 doi:10.1186/1550-2783-6-6
Mike Spillane (micheilspillane@hotmail.com)
Ryan Schoch (rschoch@purdue.edu)
Matt Cooke (matt_cooke@baylor.edu)
Travis Harvey (Travis.Harvey@usma.edu)
Mike Greenwood (mike_greenwood@baylor.edu)
Richard Kreider (rkreider@hlkn.tamu.edu)
Darryn S Willoughby (darryn_willoughby@baylor.edu)
ISSN 1550-2783
Article type Research article
Submission date 29 December 2008
Acceptance date 19 February 2009
Publication date 19 February 2009



Abstract
Numerous creatine formulations have been developed primarily to maximize creatine
absorption. Creatine ethyl ester is alleged to increase creatine bio-availability. This study
examined how a seven-week supplementation regimen combined with resistance training
affected body composition, muscle mass, muscle strength and power, serum and muscle
creatine levels, and serum creatinine levels in 30 non-resistance-trained males. In a
double-blind manner, participants were randomly assigned to a maltodextrose placebo
(PLA), creatine monohydrate (CRT), or creatine ethyl ester (CEE) group. The
supplements were orally ingested at a dose of 0.30 g/kg fat-free body mass
(approximately 20 g/day) for five days followed by ingestion at 0.075 g/kg fat free mass
(approximately 5 g/day) for 42 days. Results showed significantly higher serum creatine
concentrations in PLA (p = 0.007) and CRT (p = 0.005) compared to CEE. Serum
creatinine was greater in CEE compared to the PLA (p = 0.001) and CRT (p = 0.001) and
increased at days 6, 27, and 48. Total muscle creatine content was significantly higher in
CRT (p = 0.026) and CEE (p = 0.041) compared to PLA, with no differences between
CRT and CEE. Significant changes over time were observed for body composition, body
water, muscle strength and power variables, but no significant differences were observed
between groups. In conclusion, when compared to creatine monohydrate, creatine ethyl
ester was not as effective at increasing serum and muscle creatine levels or in improving
body composition, muscle mass, strength, and power. Therefore, the improvements in
these variables can most likely be attributed to the training protocol itself, rather than the
supplementation regimen.

Η παραπάνω έρευνα έδειξε ότι η μονουδρική κρεατίνη είναι πιο αποτελεσματική της αιθύλ-εστερικής.

Επειδή το abstract μπερδεύει λίγο τα πράγματα , το full text είναι εδώ

http://www.jissn.com/content/pdf/1550-2783-6-6.pdf