Μιας και κυκλοφορει ακομα αυτος ο μυθος σχετικα με την κρεατίνη, ειπα να ξεκινησω εδω ενα νεο θεμα με ερευνες πανω στο θεμα ασφαλειας της κρεατινης και νεφρα/νεφρικες λειτουργιες (σε υγιη ατομα παντα).
Η πρωτη ερευνα απαντα στο ερωτημα εαν η μακροχρονια ληψη κρεατινης χειροτερευει τη νεφρικη λειτουργια, σε ηδη προπονημενα ατομα, τα οποια καταναλωναν υψηλη ποσοτητα πρωτεινων.
Το συμπερασμα ηταν οτι ληψη κρεατινης για 12 εβδομαδες δεν επηρεασε τα νεφρα, πραγμα το οποιο ισχυροποιει την ασφαλεια του συμπληρωματος διατροφης.
---
Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet?
Rebeca Lugaresi, Marco Leme, V?tor de Salles Painelli, Igor Hisashi Murai, Hamilton Roschel, Marcelo Tatit Sapienza, Antonio Herbert Lancha Junior and Bruno GualanoEmail author
Journal of the International Society of Sports Nutrition 201310:26
Background
The aim of this study was to determine the effects of creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet.
Methods
A randomized, double-blind, placebo-controlled trial was performed. The participants were randomly allocated to receive either creatine (20 g/d for 5 d followed by 5 g/d throughout the trial) or placebo for 12 weeks. All of the participants were engaged in resistance training and consumed a high-protein diet (i.e., ? 1.2 g/Kg/d). Subjects were assessed at baseline (Pre) and after 12 weeks (Post). Glomerular filtration rate was measured by 51Cr-EDTA clearance. Additionally, blood samples and a 24-h urine collection were obtained for other kidney function assessments.
Results
No significant differences were observed for 51Cr-EDTA clearance throughout the trial (Creatine: Pre 101.42?±?13.11, Post 108.78?±?14.41 mL/min/1.73m2; Placebo: Pre 103.29?±?17.64, Post 106.68?±?16.05 mL/min/1.73m2; group x time interaction: F?=?0.21, p?=?0.64). Creatinine clearance, serum and urinary urea, electrolytes, proteinuria, and albuminuria remained virtually unchanged.
Conclusions
A 12-week creatine supplementation protocol did not affect kidney function in resistance-trained healthy individuals consuming a high-protein diet; thus reinforcing the safety of this dietary supplement.
Bookmarks